Everyone says NAC can make glutathione. Wrong. Evidence against this is staring right at you. As you can see here, my wife's GCLC gene is genetically slower. Thus, she cannot convert Cysteine What is Glutathione? GoldBio Glutathione Synthase an overview ScienceDirect Topics GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging The Glutamylcysteine SynthetaseGlutathione Synthetase: Domain Structure and Identification of Residues Important in Substrate and Glutathione Binding Biochemistry