Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Histopathological Findings of a Melanocytic Nevus A melanocytic nevus is a benign proliferation of melanocytes. Under the microscope, typical features include: Nests or clusters of uniform melanocytes located at the dermoepidermal junction, Pathology Outlines Melanotic macule New and evolving concepts of melanocytic nevi and melanocytomas Modern Pathology