Lets do my first B12 injection together This is something Ive been nervous about for a long time, but today I finally did itand it honestly wasnt bad at all. I used the Union Medico needle guide Self injecting vitamin B12. Quick and painless jabs after a B12 by Dr Caroline Palmer Medium Subcutaneous (SC) and Intramuscular (IM) Injections Must Knows for Subcutaneous administration: Pinch skin with non dominant hand and hold syringe with dominant hand Always inject: 2 inches away from umbilicus (for abdomen) 3 inches Compounded Methylcobalamin (Vitamin B12) Injection, 5mg mL Subcutaneous Injection: What It Is and How to Give One