Sulforaphane boosts our natural cellular defenses. It does this by activating Nrf2, our body's primary detoxification, anti inflammatory, and antioxidant pathway. Nrf2 turns on phase 2 detoxification enzymes, helping us deal with daily Multifaceted Roles of Glutathione and Glutathione Based Systems in Carcinogenesis and Anticancer Drug Resistance Elie Hatem, Nadine El Banna, Meng Er Huang, 2017 Nrf2 knockdown prevents NFT dependent elevation of glutathione levels. Download Scientific Diagram Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2 Expressing Glia Potently Protects Neurons from Oxidative Stress Journal of Neuroscience Enhanced B Raf mediated NRF2 gene transcription and HATs mediated NRF2 protein acetylation contributes to ABCC1 mediated chemoresistance and glutathione mediated survival in acquired topoisomerase II poison resistant cancer cells ScienceDirect