Vaping 0 Nicotine While Pregnant Pregnancy and Vaping CIMCC Smoking and vaping during pregnancy increase the risk of preterm birth support is available to help you quit. Smoking during pregnancy is the biggest modifiable risk factor for preterm birth. Quitting Vaping more effective than patches for pregnant women, study finds Dr Colin Mendelsohn Many people think vaping is a safer option during pregnancy. But both smoking and vaping can affect a baby's oxygen, growth, and development. Here are some risks every expecting parent should know..